A mathematical model of different multiple sclerosis variants
October 2017
University of Barcelona, Barcelona, Spain
The authors developed a mathematical model to simulate the biological processes involved in the progression of multiple sclerosis (MS) by evaluating patient data from 20 years. The results of this model were supported by pathological findings and suggested a common pathogenesis for the different MS subtypes, leading to a variety of clinical outcomes in different patient groups. This model is more meaningful to humans than animal experiments because it can predict different disease courses in patients.
Dynamics and heterogeneity of brain damage in multiple sclerosis
Pablo Villoslada
Added on: 05-25-2020
[1] https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005757